HIV-1, interferon and the interferon regulatory factor system: An interplay between induction, antiviral responses and viral evasion
Abstract
Thirty years after the first isolation of the etiological agent of AIDS, the virus HIV-1 is still a major threat worldwide with millions of individuals currently infected. Although current combination therapies allow viral replication to be controlled, HIV-1 is not eradicated and persists in drug- and immune system-insensitive reservoirs and a cure is still lacking. Pathogens such as HIV-1 that cause chronic infections are able to adapt to the...
Paper Details
Title
HIV-1, interferon and the interferon regulatory factor system: An interplay between induction, antiviral responses and viral evasion
Published Date
Aug 1, 2012
Volume
23
Issue
4-5
Pages
255 - 270
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