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References44
Newest
Published on Feb 1, 2003in Clinica Chimica Acta2.73
Cahide Gokkusu11
Estimated H-index: 11
(Istanbul University),
Tannaz Mostafazadeh1
Estimated H-index: 1
(Istanbul University)
Background: Free radical-mediated oxidative stress has been implicated in the genesis and progression of atherosclerosis. Methods: The lipid peroxides and antioxidant status of various tissues were investigated in hypercholesterolemic rats and the effect of vitamin E supplementation on defense systems. Results: Cholesterol-feeding caused a significant increase in the lipid peroxide concentrations of plasma, erythrocytes, liver and brain. In addition, a significant decrease in glutathione (GSH) c...
Evin Ademoglu17
Estimated H-index: 17
,
Cahide Gokkusu11
Estimated H-index: 11
,
Sükrü Palandüz1
Estimated H-index: 1
It has been shown that the lipid composition of plasma membrane can be modified in vivo by dietary fat. It has also been observed that an increase in the cholesterol content of plasma membranes results in decreased activities of ATPases. In the present study, we evaluated the changes in the activities of ATPases from erythrocytes, hepatocytes, and kidney cortex caused by cholesterol-rich diet in rats and subsequently examined the role of vitamin E administration on the cholesterol-induced effect...
Published on Nov 1, 1999in Free Radical Biology and Medicine5.66
Helmut Sies111
Estimated H-index: 111
(HHU: University of Düsseldorf)
Abstract Glutathione (GSH) is the major cellular thiol participating in cellular redox reactions and thioether formation. This article serves as introduction to the FRBM Forum on glutathione and emphasizes cellular functions: What is GSH? Where does it come from? Where does it go? What does it do? What is new and noteworthy? Research tools, historical remarks, and links to current trends.
Published on Sep 1, 1997in Clinica Chimica Acta2.73
D. Mazor1
Estimated H-index: 1
(BGU: Ben-Gurion University of the Negev),
G. Brill1
Estimated H-index: 1
+ 2 AuthorsN. Meyerstein1
Estimated H-index: 1
(BGU: Ben-Gurion University of the Negev)
Cahide Gokkusu11
Estimated H-index: 11
(Istanbul University),
Evin Ademoglu17
Estimated H-index: 17
(Istanbul University)
+ 1 AuthorsÜmit Türkoğlu8
Estimated H-index: 8
(Istanbul University)
Published on Aug 1, 1996in Life Sciences3.45
Cahide Gokkusu11
Estimated H-index: 11
(Istanbul University),
Evin Ademoglu17
Estimated H-index: 17
(Istanbul University)
+ 2 AuthorsFahrettin Oz8
Estimated H-index: 8
(Istanbul University)
Abstract The thymus hormones were reported to be effective on lipid peroxidation and the antioxidant system. Thymus plays a broader role than just regulating the immune system. Thymosin α 1 is the first subgroup extracted from thymosin F5 and has higher biological activity than thymosin F5. In the present study, we have examined the effects of thymosin α 1 on lipid levels and lipid peroxidation and glutathione (GSH) content in the plasma, liver and aorta tissues of atherosclerotic rabbits. At th...
Published on Feb 1, 1996in Biochemical Pharmacology4.83
Troy T. Rohn6
Estimated H-index: 6
(UW: University of Washington),
Thomas R. Hinds23
Estimated H-index: 23
(UW: University of Washington),
Frank F. Vincenzi21
Estimated H-index: 21
(UW: University of Washington)
Abstract Preincubation of red blood cell (RBC) membranes with a model system known to generate reactive oxygen species (ROS) and free radicals (200 μM ferrous sulfate and 200 μM EDTA, Fe 2+ /EDTA) resulted in inhibition of the Na + K + - pump ATPase, the basal Ca 2+ -pump ATPase, and the calmodulin-activated Ca 2+ -pump ATPase. Inhibition of the ion pump ATPases was also associated with membrane protein crosslinking and lipid peroxidation, the latter as monitored by the formation of thiobarbitur...
Published on Nov 1, 1995in Redox Report1.96
O. Lux1
Estimated H-index: 1
,
D. Naidoo1
Estimated H-index: 1
SUMMARYThe enzymatic antioxidant defences of mammalian cells include copper-zinc superoxide dismutase (SOD)(Cu Zn-SOD; EC 1.15.1.1) which catalyses the dismutation of superoxide anions (O2.-) to hydrogen peroxide(H2, O2)and a seleno-dependent glutathione peroxidase (GSH-px) (GSH-px; EC 1.11.1.9) which catalyses the degradation of H2O2 to H2O and O2. The measurement of these enzyme activities is often used as a possible biological index of oxidative stress in various clinical conditions. Complete...
Published on Nov 1, 1994in Journal of Nutrition4.42
Diane W. Morel11
Estimated H-index: 11
(Drexel University),
Margarita de la Llera-Moya1
Estimated H-index: 1
(Drexel University),
Karen E. Friday1
Estimated H-index: 1
(Drexel University)
New Zealand White rabbits were made hypercholesterolemic by feeding a high cholesterol diet (10 g/kg diet) with or without added antioxidants. The antioxidants used were either probucol (10 g/kg) or vitamin E (10 g/kg) plus vitamin C (0.6 g/kg). Serum cholesterol concentrations were monitored as a function of time. At the end of 10 wk, serum and lipoprotein vitamin E concentrations, the extent of oxidation of lipoprotein fractions (thiobarbituric acid reacting substances), the susceptibility of ...
Cited By3
Newest
Ahmad Nazrun Shuid16
Estimated H-index: 16
,
Sharlina Mohamad5
Estimated H-index: 5
(UKM: National University of Malaysia)
+ 3 AuthorsIma Nirwana Soelaiman18
Estimated H-index: 18
K.G. Nevin1
Estimated H-index: 1
(UoK: University of Kerala),
T. Rajamohan1
Estimated H-index: 1
(UoK: University of Kerala)
Summary Background aims Experimental and epidemiological studies indicate an association between dietary saturated fatty acids and thrombosis, but the effects of individual fatty acids on haemostasis are still controversial. The purpose of this research is to evaluate the effect of feeding virgin coconut oil (VCO) on blood coagulation factors, lipid levels and in vitro oxidation of LDL in comparison with copra oil (CO) and sunflower oil (SFO) in cholesterol (1%) and oil (10% w/w) fed rats. Metho...