A Novel Approach to Establishing the Design Space for the Oral Formulation Manufacturing Process

Volume: 61, Issue: 1, Pages: 39 - 49
Published: Jan 1, 2013
Abstract
A novel approach to establishing the design space for the oral formulation manufacturing process was investigated. A response surface method incorporating multivariate spline interpolation was applied to overcome the nonlinear problem, which is always problematic in pharmaceutical development studies, and a bootstrap resampling technique, polynomial approximation technique, and 95% confidence intervals based on a nonparametric approach were...
Paper Details
Title
A Novel Approach to Establishing the Design Space for the Oral Formulation Manufacturing Process
Published Date
Jan 1, 2013
Volume
61
Issue
1
Pages
39 - 49
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.