Extracellular DNA traps promote thrombosis

Volume: 107, Issue: 36, Pages: 15880 - 15885
Published: Sep 7, 2010
Abstract
Neutrophil extracellular traps (NETs) are part of the innate immune response to infections. NETs are a meshwork of DNA fibers comprising histones and antimicrobial proteins. Microbes are immobilized in NETs and encounter a locally high and lethal concentration of effector proteins. Recent studies show that NETs are formed inside the vasculature in infections and noninfectious diseases. Here we report that NETs provide a heretofore unrecognized...
Paper Details
Title
Extracellular DNA traps promote thrombosis
Published Date
Sep 7, 2010
Volume
107
Issue
36
Pages
15880 - 15885
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