Nucleophosmin may act as an alarmin: implications for severe sepsis.

Volume: 86, Issue: 3, Pages: 645 - 653
Published: Sep 1, 2009
Abstract
NPM is a major nucleolar multifunctional protein involved in ribosome biogenesis, centrosome duplication, cell-cycle progression, apoptosis, cell differentiation, and sensing cellular stress. Alarmins are endogenous molecules released from activated cells and/or dying cells, which activate the immune system and cause severe damage to cells and tissue organs. In the present work, stimulation of cells with the alarmin-inducible molecule endotoxin,...
Paper Details
Title
Nucleophosmin may act as an alarmin: implications for severe sepsis.
Published Date
Sep 1, 2009
Volume
86
Issue
3
Pages
645 - 653
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