Planarian MBD2/3 is required for adult stem cell pluripotency independently of DNA methylation
Abstract
Planarian adult stem cells (pASCs) or neoblasts represent an ideal system to study the evolution of stem cells and pluripotency as they underpin an unrivaled capacity for regeneration. We wish to understand the control of differentiation and pluripotency in pASCs and to understand how conserved, convergent or divergent these mechanisms are across the Bilateria. Here we show the planarian methyl-CpG Binding Domain 2/3 (mbd2/3) gene is required...
Paper Details
Title
Planarian MBD2/3 is required for adult stem cell pluripotency independently of DNA methylation
Published Date
Dec 1, 2013
Journal
Volume
384
Issue
1
Pages
141 - 153
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