Telomere attrition and genomic instability in xeroderma pigmentosum type-b deficient fibroblasts under oxidative stress

Volume: 14, Issue: 1-2, Pages: 403 - 416
Published: Oct 16, 2009
Abstract
Xeroderma pigmentosum B (XPB/ERCC3/p89) is an ATP-dependent 3′→5′ directed DNA helicase involved in basal RNA transcription and the nucleotide excision repair (NER) pathway. While the role of NER in alleviating oxidative DNA damage has been acknowledged it remains poorly understood. To study the involvement of XPB in repair of oxidative DNA damage, we utilized primary fibroblasts from a patient suffering from XP with Cockayne syndrome and...
Paper Details
Title
Telomere attrition and genomic instability in xeroderma pigmentosum type-b deficient fibroblasts under oxidative stress
Published Date
Oct 16, 2009
Volume
14
Issue
1-2
Pages
403 - 416
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.