Binding of serum response factor to cystic fibrosis transmembrane conductance regulator CArG-like elements, as a new potential CFTR transcriptional regulation pathway

Volume: 33, Issue: 16, Pages: 5271 - 5290
Published: Sep 7, 2005
Abstract
CFTR expression is tightly controlled by a complex network of ubiquitous and tissue-specific cis -elements and trans -factors. To better understand mechanisms that regulate transcription of CFTR , we examined transcription factors that specifically bind a CFTR CArG-like motif we have previously shown to modulate CFTR expression. Gel mobility shift assays and chromatin immunoprecipitation analyses demonstrated the CFTR CArG-like motif binds serum...
Paper Details
Title
Binding of serum response factor to cystic fibrosis transmembrane conductance regulator CArG-like elements, as a new potential CFTR transcriptional regulation pathway
Published Date
Sep 7, 2005
Volume
33
Issue
16
Pages
5271 - 5290
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