Heritability of Pancreatic β-Cell Function among Nondiabetic Members of Caucasian Familial Type 2 Diabetic Kindreds1
Volume: 84, Issue: 4, Pages: 1398 - 1403
Published: Apr 1, 1999
Abstract
Both defective insulin secretion and insulin resistance have been reported in relatives of type 2 diabetic subjects. We tested 120 members of 26 families with a type 2 diabetic sibling pair with a tolbutamide-modified, frequently sampled iv glucose tolerance test to determine the insulin sensitivity index (SI) and acute insulin response to glucose (AIRglucose). A measure ofβ -cell compensation for insulin sensitivity was calculated as the...
Paper Details
Title
Heritability of Pancreatic β-Cell Function among Nondiabetic Members of Caucasian Familial Type 2 Diabetic Kindreds1
Published Date
Apr 1, 1999
Volume
84
Issue
4
Pages
1398 - 1403
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