Histone deacetylase 4 selectively contributes to podocyte injury in diabetic nephropathy
Abstract
Studies have highlighted the importance of histone deacetylase (HDAC)-mediated epigenetic processes in the development of diabetic complications. Inhibitors of HDAC are a novel class of therapeutic agents in diabetic nephropathy, but currently available inhibitors are mostly nonselective inhibit multiple HDACs, and different HDACs serve very distinct functions. Therefore, it is essential to determine the role of individual HDACs in diabetic...
Paper Details
Title
Histone deacetylase 4 selectively contributes to podocyte injury in diabetic nephropathy
Published Date
Oct 1, 2014
Journal
Volume
86
Issue
4
Pages
712 - 725
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