Identification of two novelShank3transcripts in the developing mouse neocortex

Volume: 128, Issue: 2, Pages: 280 - 293
Published: Nov 14, 2013
Abstract
SHANK3 is a synaptic scaffolding protein enriched in the post-synaptic density of excitatory synapses. Since several SHANK3 mutations have been identified in a particular phenotypic group of patients with autism spectrum disorder (ASD), SHANK3 is strongly suspected of being involved in the pathogenesis and neuropathology of ASD. Several SHANK3 isoforms are known to be produced in the developing brain, but they have not been fully investigated....
Paper Details
Title
Identification of two novelShank3transcripts in the developing mouse neocortex
Published Date
Nov 14, 2013
Volume
128
Issue
2
Pages
280 - 293
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