Bone remodelling in osteoarthritis
Abstract
The classical view of the pathogenesis of osteoarthritis (OA) is that subchondral sclerosis is associated with, and perhaps causes, age-related joint degeneration. Recent observations have demonstrated that OA is associated with early loss of bone owing to increased bone remodelling, followed by slow turnover leading to densification of the subchondral plate and complete loss of cartilage. Subchondral densification is a late event in OA that...
Paper Details
Title
Bone remodelling in osteoarthritis
Published Date
Aug 7, 2012
Journal
Volume
8
Issue
11
Pages
665 - 673
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Notes
History