Detection of Phosphatidylcholine Hydroperoxide Produced in the Heart of the Doxorubicin Administered Mouse
Abstract
A chemiluminescence(CL)-high performance liquid chromatography (HPLC) system, where CL detector was equipped with normal phase HPLC, was used in order to specifically detect lipid hydroperoxide in the heart of doxorubicin (DXR) administered mice. Luminol and cytochrome c were used as the luminescence reagents specific for the hydroperoxide. Phosphatidylcholine hydroperoxide was detected in the heart, indicating participation of lipid...
Paper Details
Title
Detection of Phosphatidylcholine Hydroperoxide Produced in the Heart of the Doxorubicin Administered Mouse
Published Date
Jun 1, 1997
Journal
Volume
30
Issue
8
Pages
1483 - 1490
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