Potential Cancer Chemopreventive Activity of Protocatechuic Acid

A natural phenolic compound, protocatechuic acid (3,4-dihydroxybenzoic acid), is present in many edible and medicinal plants. Recent studies, including our animal experiments, indicate that this simple phenolic acid could be protective against the development of epithelial malignancy in different tissues and cardiovascular diseases as well. The mechanism of the action is mostly associated with antioxidant activity, including inhibition of...