MiR-204 regulates cardiomyocyte autophagy induced by ischemia-reperfusion through LC3-II
Abstract
Background Autophagy plays a significant role in myocardial ischemia-reperfusion (IR) injury. So it is important to inhibit autophagy to protect cardiomyocytes besides anti-apoptosis. MiRNA has been demonstrated to protect cardiomyocytes against apoptosis during IR, while whether it has anti-autophagy effect has not been known. The aim of this study was to investigate whether miR-204 regulated autophagy by regulating LC3-II protein, which is the...
Paper Details
Title
MiR-204 regulates cardiomyocyte autophagy induced by ischemia-reperfusion through LC3-II
Published Date
Jun 1, 2011
Volume
18
Issue
1
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