Trans Fatty Acids: Are Its Cardiovascular Risks Fully Appreciated?

Paul J. Nestel

doi:https://doi.org/10.1016/j.clinthera.2014.01.020

doi.org/10.1016/j.clinthera.2014.01.020

Trans Fatty Acids: Are Its Cardiovascular Risks Fully Appreciated?

Paul J. Nestel

72

Clinical Therapeutics3.20

Volume: 36, Issue: 3, Pages: 315 - 321

Published: Mar 1, 2014

Abstract

The goal of this article was to review the causal link between trans fatty acids (TFA) produced from partially hydrogenated vegetable oil (PHVO) and cardiovascular disease (CVD) risk and its likely mechanisms. The potential risk of TFA from ruminant dairy and meats, which are currently the major sources of dietary TFA, is also discussed.Evidence was derived from observational studies of large cohorts followed up prospectively; from randomized...