Synthesis, Structural Characterization, and Initial Evaluation as Anticancer Drugs of Dibutyltin Polyamines Derived from Various 4,6-Diaminopyrimidines

A number of diaminopyrimidines have been incorporated into dibutyltin polyamines with molecular weights ranging from 3.5 × 104 to 3.7 × 106 and product yields from 47 to 88%. Infrared spectroscopy is consistent with the inclusion of the diaminopyridines into the polymer backbone with the IR spectroscopy showing the formation of the Sn–N bond as well as the presence of bands from both reactants being present in the polymer. F MALDI MS is also...