Short syntheses of 1,2,3,5-tetrahydro-5-oxopyrrolo-[1,2-a]quinoline-4-carboxylic acid and 1,2,3,4-tetrahydro-6H-6-oxopyrido[1,2-a]quinoline-5-carboxylic acid derivatives

Short and efficient syntheses of 7‐fluoro‐8‐(4‐methylpiperazin‐1‐yl)‐1,2,3,5‐tetrahydro‐5‐oxopyrrolo[1,2‐ a ]‐quinoline‐4‐carboxylic acid and 8‐fluoro‐9‐(4‐methylpiperazin‐1‐yl)‐1,2,3,4‐tetrahydro‐6 H ‐6‐oxopyrido[1,2‐ a ]‐quinoline‐5‐carboxylic acid are described. Both basic heterocycles were synthesized in two steps by the condensation of a benzoylacetate with an imino ether followed by an intramolecular nucleophilic displacement cyclization...