Review paper
Assessment of Pancreatic β-Cell Function: Review of Methods and Clinical Applications
Abstract
Type 2 diabetes mellitus (T2DM) is characterized by a progressive failure of pancreatic β-cell function (BCF) with insulin resistance. Once insulin over-secretion can no longer compensate for the degree of insulin resistance, hyperglycemia becomes clinically significant and deterioration of residual β-cell reserve accelerates. This pathophysiology has important therapeutic implications. Ideally, therapy should address the underlying pathology...
Paper Details
Title
Assessment of Pancreatic β-Cell Function: Review of Methods and Clinical Applications
Published Date
Mar 31, 2014
Journal
Volume
10
Issue
1
Pages
2 - 42
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