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Published on Jan 1, 1996in The Lancet 59.10
· DOI :10.5555/uri:pii:S0140673696904559
Ian A. Cree41
Estimated H-index: 41
(UCL: University College London),
A.J.E. Foss1
Estimated H-index: 1
(UCL: University College London)
+ 1 AuthorsPeter McCulloch38
Estimated H-index: 38
(University of Liverpool)
  • References (4)
  • Citations (2)
Published on Nov 1, 1995in The Lancet 59.10
P. McCulloch1
Estimated H-index: 1
(RLUH: Royal Liverpool University Hospital),
A. Choy1
Estimated H-index: 1
(RLUH: Royal Liverpool University Hospital),
L. Martin1
Estimated H-index: 1
(RLUH: Royal Liverpool University Hospital)
Abstract Tumour angiogenesis is a powerful prognostic indicator in breast cancer. Shedding of tumour cells into the bloodstream is essential for haematogenous metastasis. The relation between cell shedding and angiogenesis in human cancer is not known. We studied vascular density and cell shedding in 16 women undergoing breast cancer surgery. Circulating cells were found in one patient before, in six during, and none after operation. Vascular density was related to detection of circulating tumou...
86 Citations Source Cite
Published on Jul 1, 1995in British Journal of Cancer 5.42
Alexander J. E. Foss24
Estimated H-index: 24
Matthew Guille17
Estimated H-index: 17
+ 3 AuthorsSusan Lightman55
Estimated H-index: 55
Both cutaneous and uveal melanoma undergo haematogenous dissemination. Detection of tyrosinase mRNA by reverse transcription-polymerase chain reaction (RT-PCR) has been described as an extremely sensitive way of detecting circulating viable melanoma cells in the peripheral venous blood, and this technique may be of value in the early detection of dissemination. Also, it has been suggested that surgical manipulation of the eye, such as occurs during enucleation, can provoke uveal melanoma dissemi...
136 Citations Source Cite
Published on Jan 3, 1991in The New England Journal of Medicine 70.67
Noel Weidner18
Estimated H-index: 18
Joseph P. Semple2
Estimated H-index: 2
+ 1 AuthorsJudah Folkman150
Estimated H-index: 150
Abstract Background. Experimental evidence suggests that the growth of a tumor beyond a certain size requires angiogenesis, which may also permit metastasis. To investigate how tumor angiogenesis correlates with metastases in breast carcinoma, we counted microvessels (capillaries and venules) and graded the density of microvessels within the initial invasive carcinomas of 49 patients (30 with metastases and 19 without). Methods. Using light microscopy, we highlighted the vessels by staining thei...
4,688 Citations Source Cite
Published on Apr 1, 1989in The Lancet 59.10
D.W. Sadler1
Estimated H-index: 1
S.B. Coghill1
Estimated H-index: 1
19 Citations Source Cite
Cited By2
Published on Dec 1, 2018in Modern Pathology 6.37
Guido Rindi63
Estimated H-index: 63
(UCSC: Catholic University of the Sacred Heart),
David S. Klimstra107
Estimated H-index: 107
(MSK: Memorial Sloan Kettering Cancer Center)
+ 23 AuthorsAdel El-K. Naggar103
Estimated H-index: 103
(University of Texas MD Anderson Cancer Center)
The classification of neuroendocrine neoplasms (NENs) differs between organ systems and currently causes considerable confusion. A uniform classification framework for NENs at any anatomical location may reduce inconsistencies and contradictions among the various systems currently in use. The classification suggested here is intended to allow pathologists and clinicians to manage their patients with NENs consistently, while acknowledging organ-specific differences in classification criteria, tum...
16 Citations Source Cite
Published on Jul 1, 2004in Histopathology 3.29
Mudhar Hs1
Estimated H-index: 1
(University of Sheffield),
M A Parsons13
Estimated H-index: 13
(University of Sheffield)
+ 3 AuthorsIan G. Rennie30
Estimated H-index: 30
(University of Sheffield)
45 Citations Source Cite