Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA
Abstract
Overlapping complementary DNA clones were isolated from epithelial cell libraries with a genomic DNA segment containing a portion of the putative cystic fibrosis (CF) locus, which is on chromosome 7. Transcripts, approximately 6500 nucleotides in size, were detectable in the tissues affected in patients with CF. The predicted protein consists of two similar motifs, each with (i) a domain having properties consistent with membrane association and...
Paper Details
Title
Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA
Published Date
Sep 8, 1989
Journal
Volume
245
Issue
4922
Pages
1066 - 1073
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