Stagewise, group sequential experimental designs for quantal responses. one-sample and two-sample comparisons.

Volume: 15, Issue: 1, Pages: 129 - 133
Published: Mar 1, 1991
Abstract
The use of stagewise, group sequential experimental designs with dichotomous responses in toxicity or drug screening programs is discussed. Such designs represent a compromise between the standard, fixed sample size designs and fully sequential designs. Stagewise group sequential designs place specified numbers of animals on test at each stage, up to a maximum number of stages. The greatest increases in sample size efficiency occur with small...
Paper Details
Title
Stagewise, group sequential experimental designs for quantal responses. one-sample and two-sample comparisons.
Published Date
Mar 1, 1991
Volume
15
Issue
1
Pages
129 - 133
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