Endocrine and metabolic effects of consuming beverages sweetened with fructose, glucose, sucrose, or high-fructose corn syrup

Our laboratory has investigated 2 hypotheses regarding the effects of fructose consumption:1) the endocrine effects of fructose consumption favor a positive energy balance, and2) fructose consumption promotes the development of an atherogenic lipid profile. In previous short- and long-term studies, we showed that consumption of fructose-sweetened beverages with 3 meals results in lower 24-h plasma concentrations of glucose, insulin, and leptin...