Modulatory Effects of Atorvastatin on Endothelial Cell–Derived Chemokines, Cytokines, and Angiogenic Factors

Study Objective . To investigate the immunomodulatory effects of 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase inhibitors (statins) by determining whether atorvastatin alters the production of specific endothelium‐derived immunoactive proteins and whether its treatment effects depend on its concentration and/or inhibition of 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase. Design . In vitro study using a multiplexing method for protein...