Genome-wide transcription profile of field- and laboratory-selected dichlorodiphenyltrichloroethane (DDT)-resistant Drosophila

Genome-wide microarray analysis (Affymetrix array) was used ( i ) to determine whether only one gene, the cytochrome P450 enzyme Cyp6g1 , is differentially transcribed in dichlorodiphenyltrichloroethane (DDT)-resistant vs. -susceptible Drosophila ; and ( ii ) to profile common genes differentially transcribed across a DDT-resistant field isolate [ Rst(2)DDT Wisconsin ] and a laboratory DDT-selected population [ Rst(2)DDT 91-R ]. Statistical...