A Simple Model Predicting Individual Weight Change in Humans.

Published on Nov 1, 2011in Journal of Biological Dynamics1.642
· DOI :10.1080/17513758.2010.508541
Diana M. Thomas31
Estimated H-index: 31
(MSU: Montclair State University),
Corby K. Martin49
Estimated H-index: 49
(Pennington Biomedical Research Center)
+ 3 AuthorsJames A. Levine63
Estimated H-index: 63
(Mayo Clinic)
Excessive weight in adults is a national concern with over 2/3 of the US population deemed overweight. Because being overweight has been correlated to numerous diseases such as heart disease and type 2 diabetes, there is a need to understand mechanisms and predict outcomes of weight change and weight maintenance. A simple mathematical model that accurately predicts individual weight change offers opportunities to understand how individuals lose and gain weight and can be used to foster patient adherence to diets in clinical settings. For this purpose, we developed a one-dimensional differential equation model of weight change based on the energy balance equation paired to an algebraic relationship between fat-free mass and fat mass derived from a large nationally representative sample of recently released data collected by the Centers for Disease Control. We validate the model's ability to predict individual participants’ weight change by comparing model estimates of final weight data from two recent unde...
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