Rituximab and Immune Deficiency: Case Series and Review of the Literature

Background As the indications and use of rituximab continue to expand, the reports of long-term effects of anti-CD20–mediated B-cell depletion on the immune system accumulate. Objective We report a group of patients with immunodeficiency who were treated with rituximab and present their immunologic data. Methods A retrospective chart review identified patients with immunodeficiency who received rituximab for treatment of their primary disease...