Lipids and Lipoproteins and Risk of Different Vascular Events in the MRC/BHF Heart Protection Study

Background— Low-density lipoprotein (LDL) cholesterol and high-density lipoprotein (HDL) cholesterol are established risk factors for vascular disease, but lipoprotein particle concentrations may be stronger determinants of risk. Methods and Results— Associations between vascular events and baseline concentrations of cholesterol fractions, apolipoproteins B and A 1 , and lipoprotein particles assessed by nuclear magnetic resonance were...