Original paper
The application of multiple reaction monitoring to assess ApoA-I methionine oxidations in diabetes and cardiovascular disease
Abstract
The oxidative modification of apolipoprotein A-I’s methionine148 (M148) is associated with defective HDL function in vitro. Multiple reaction monitoring (MRM) is a mass spectrometric technique that can be used to quantitate post-translational modifications. In this study, we developed an MRM assay to monitor the abundance ratio of the peptide containing oxidized M148 to the native peptide in ApoA-I. Measurement of the oxidized-to-unoxidized-M148...
Paper Details
Title
The application of multiple reaction monitoring to assess ApoA-I methionine oxidations in diabetes and cardiovascular disease
Published Date
Dec 1, 2014
Journal
Volume
4-5
Pages
18 - 24
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Notes
History