Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells
Abstract
Summary null Developmental fate decisions are dictated by master transcription factors (TFs) that interact with null cis -regulatory elements to direct transcriptional programs. Certain malignant tumors may also depend on cellular hierarchies reminiscent of normal development but superimposed on underlying genetic aberrations. In glioblastoma (GBM), a subset of stem-like tumor-propagating cells (TPCs) appears to drive tumor progression and...
Paper Details
Title
Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells
Published Date
Apr 24, 2014
Journal
Volume
157
Issue
3
Pages
580 - 594
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Notes
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