Towards a transgenic model of Huntington’s disease in a non-human primate

Nature64.80
Volume: 453, Issue: 7197, Pages: 921 - 924
Published: Jun 12, 2008
Abstract
Huntington's disease is a severely disabling and lethal neurodegenerative disorder. The development of a non-human primate model for the disease would be invaluable in understanding its pathology and in developing therapeutic strategies, and this paper reports a significant step towards that goal is reported in this issue. Transgenic rhesus macaque monkeys that express the first exon of the polyglutamine-expanded human huntingtin gene develop...
Paper Details
Title
Towards a transgenic model of Huntington’s disease in a non-human primate
Published Date
Jun 12, 2008
Journal
Volume
453
Issue
7197
Pages
921 - 924
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