Growth Hormone Receptor: Structure Function Relationships

Volume: 76, Issue: Suppl. 1, Pages: 12 - 16
Published: Jan 1, 2011
Abstract
<i>Background:</i> The growth hormone receptor (GHR) was the first class 1 cytokine receptor to be cloned, and it has been studied intensively. The crystal structures of the bound and unbound forms have been solved and the energetic contributions of residues involved in the binding interaction have been quantified. Two receptor subunits bind to opposite sides of the hormone through site 1 and site 2, and a third interaction occurs...
Paper Details
Title
Growth Hormone Receptor: Structure Function Relationships
Published Date
Jan 1, 2011
Volume
76
Issue
Suppl. 1
Pages
12 - 16
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