A systematic review and meta-analysis of glucocorticoid-induced osteoporosis in children

To summarize the published effects of systemic glucocorticoid therapy on bone mineral density (BMD) and fractures in children. We performed a systematic review and meta-analysis of existing literature, using Medline, CINAHL, and Cochrane databases to identify studies of BMD or fractures in children ≤18 years taking systemic glucocorticoid therapy. We excluded studies of inhaled glucocorticoids, chemotherapy, and organ transplantation. Two...