Exploration of glycosylated-organotin(IV) complexes as anticancer drug candidates

Volume: 423, Pages: 38 - 45
Published: Nov 1, 2014
Abstract
The design of metal-based chemotherapeutic drugs depends on choice of ligand framework, therefore, metals incorporated in a bioactive ligand scaffold hold promise for the improved pharmacokinetic profile and better efficacy of drugs. In this context, glycosylated-organotin(IV) antitumor agents are attractive and prove the state-of-the-art design for chemotherapy due to organotin-induced cytotoxicity. In recent years, many organotin(IV) complexes...
Paper Details
Title
Exploration of glycosylated-organotin(IV) complexes as anticancer drug candidates
Published Date
Nov 1, 2014
Volume
423
Pages
38 - 45
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