Crack cocaine, disease progression, and mortality in a multicenter cohort of HIV-1 positive women
Abstract
Recent research suggests that cocaine may directly affect the pathobiology of HIV by causing immune alterations in different lymphocytes such as helper T cells (CD4), suppressor/cytotoxic T cells (CD8), and natural killer (NK) cells.1 Studies show that cocaine interferes with the body’s ability to defend against infection by inhibiting the effector functions of neutrophils and macrophages, and by suppressing cytokine production, decreasing...
Paper Details
Title
Crack cocaine, disease progression, and mortality in a multicenter cohort of HIV-1 positive women
Published Date
Jul 11, 2008
Journal
Volume
22
Issue
11
Pages
1355 - 1363
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Notes
History