Structure of human desArg-C5a
Volume: 66, Issue: 2, Pages: 190 - 197
Published: Jan 22, 2010
Abstract
The anaphylatoxin C5a is derived from the complement component C5 during activation of the complement cascade. It is an important component in the pathogenesis of a number of inflammatory diseases. NMR structures of human and porcine C5a have been reported; these revealed a four-helix bundle stabilized by three disulfide bonds. The crystal structure of human desArg-C5a has now been determined in two crystal forms. Surprisingly, the protein...
Paper Details
Title
Structure of human desArg-C5a
Published Date
Jan 22, 2010
Volume
66
Issue
2
Pages
190 - 197
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