Original paper
Mouse tetrad analysis provides insights into recombination mechanisms and hotspot evolutionary dynamics
Abstract
The ability to examine all chromatids from a single meiosis in yeast tetrads has been indispensable for defining the mechanisms of homologous recombination initiated by DNA double-strand breaks (DSBs). Using a broadly applicable strategy for the analysis of chromatids from a single meiosis at two recombination hotspots in mouse oocytes and spermatocytes, we demonstrate here the unidirectional transfer of information-gene conversion-in both...
Paper Details
Title
Mouse tetrad analysis provides insights into recombination mechanisms and hotspot evolutionary dynamics
Published Date
Aug 24, 2014
Journal
Volume
46
Issue
10
Pages
1072 - 1080
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Notes
History