The Influence of <b><i>BRCA1/BRCA2</i></b> Mutations on Toxicity Related to Chemotherapy and Radiotherapy in Early Breast Cancer Patients
Abstract
<b><i>Objective:</i></b> The presence of <i>BRCA</i> gene mutation and low expressions of BRCA proteins are associated with a greater sensitivity of tumor cells to ionizing radiation and to cytostatics damaging the DNA of the cells. The purpose of this study was to estimate the rate of adverse events in <i>BRCA1/2</i>-associated breast cancer patients receiving anthracycline-based chemotherapy...
Paper Details
Title
The Influence of <b><i>BRCA1/BRCA2</i></b> Mutations on Toxicity Related to Chemotherapy and Radiotherapy in Early Breast Cancer Patients
Published Date
Jan 1, 2013
Journal
Volume
85
Issue
5
Pages
278 - 282
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Notes
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