Sympathetic suppression attenuates anomalous responses to morphine in unexplained pain after cholecystectomy
Abstract
Anomalous responses to morphine are common in patients with unexplained pain in the upper abdomen after cholecystectomy and may be linked to activation of the sympathetic nervous system. The hypothesis that sympathetic suppression would attenuate anomalous responses to morphine was tested by a randomized, cross-over trial using a standard challenge with morphine, with and without pretreatment with clonidine (300 µg orally, 1 h prior to the...
Paper Details
Title
Sympathetic suppression attenuates anomalous responses to morphine in unexplained pain after cholecystectomy
Published Date
Aug 1, 1994
Journal
Volume
4
Issue
4
Pages
185 - 188
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