Effects of limb immobilization on brain plasticity

Little is known about the effects of reduced sensory input and motor output in the human brain. Therefore, we conducted a longitudinal study to investigate whether limb immobilization after unilateral arm injury is reflected in structural plastic changes in gray matter (cortical thickness) and white matter (fractional anisotropy [FA]).We examined 10 right-handed subjects with injury of the right upper extremity that required at least 14 days of...