Antithetic roles of proteoglycans in cancer
Volume: 69, Issue: 4, Pages: 553 - 579
Published: Oct 2, 2011
Abstract
Proteoglycans (PGs), a family of complex post-translationally sculptured macromolecules, are fundamental regulators of most normal and aberrant cellular functions. The unparalleled structural–functional diversity of PGs endows them with the ability to serve as critical mediators of the tumor cells’ interaction with the host microenvironment, while directly contributing to the organization and dynamic remodeling of this milieu. Despite their...
Paper Details
Title
Antithetic roles of proteoglycans in cancer
Published Date
Oct 2, 2011
Volume
69
Issue
4
Pages
553 - 579
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