Regulation of pancreatic inflammation by connective tissue growth factor (CTGF/CCN2)
Abstract
Pancreatitis is caused by long-term heavy alcohol consumption, which results in injury and death of pancreatic acinar cells (PAC). The PAC play a pivotal role in mediating early inflammatory responses but the underlying mechanisms remain poorly understood. Treatment of C57BL/6 mice with ethanol and cerulein resulted in increased staining for acinar interleukin- 1b (IL-1b), chemokine (C-C motif) ligand 3 (CCL3), or connective tissue growth factor...
Paper Details
Title
Regulation of pancreatic inflammation by connective tissue growth factor (CTGF/CCN2)
Published Date
Mar 11, 2014
Journal
Volume
141
Issue
4
Pages
564 - 576
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