Features of and Mechanisms Underlying Insulitis In <i>aly/aly</i> MaleMice as an Animal Model of Autoimmune Pancreatitis: Activation of CD11c<sup>+</sup>, CD4<sup>+</sup>, and Th2 Cells and Predominant Destruction of β-cells
Volume: 24, Issue: 2, Pages: 139 - 153
Published: Jan 1, 2012
Abstract
Diabetes mellitus (DM) is observed in patients with autoimmune pancreatitis (AIP). The development of DM in AIP is believed to be due to blood flow obstruction of the endocrine gland that accompanies pancreatitis, as well as injury to the islets caused by inflammation. The latter is called insulitis and the detailed mechanisms underlying its development are not yet clear. The aim of the present study was to elucidate the mechanisms involved in...
Paper Details
Title
Features of and Mechanisms Underlying Insulitis In <i>aly/aly</i> MaleMice as an Animal Model of Autoimmune Pancreatitis: Activation of CD11c<sup>+</sup>, CD4<sup>+</sup>, and Th2 Cells and Predominant Destruction of β-cells
Published Date
Jan 1, 2012
Volume
24
Issue
2
Pages
139 - 153
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