Cell-free expression of soluble and membrane proteins in an array device for drug screening.

Volume: 82, Issue: 16, Pages: 7021 - 7026
Published: Jul 28, 2010
Abstract
Enzymes and membrane protein receptors represent almost three-quarters of all current drug targets. As a result, it would be beneficial to have a platform to produce them in a high-throughput format for drug screening. We have developed a miniaturized fluid array device for cell-free protein synthesis, and the device was exploited to produce both soluble and membrane proteins. Two membrane-associated proteins, bacteriorhodopsin and ApoA...
Paper Details
Title
Cell-free expression of soluble and membrane proteins in an array device for drug screening.
Published Date
Jul 28, 2010
Volume
82
Issue
16
Pages
7021 - 7026
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