Osteocyte regulation of bone mineral: a little give and take
Abstract
Osteocytes actively participate in almost every phase of mineral handling by bone. They regulate the mineralisation of osteoid during bone formation, and they are also a major RANKL-producing cell. Osteocytes are thus able to liberate bone mineral by regulating osteoclast differentiation and activity in response to a range of stimuli, including bone matrix damage, bone disuse and mechanical unloading, oestrogen deficiency, high-dose...
Paper Details
Title
Osteocyte regulation of bone mineral: a little give and take
Published Date
Feb 3, 2012
Journal
Volume
23
Issue
8
Pages
2067 - 2079
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Notes
History