Reward Processing in Healthy Offspring of Parents With Bipolar Disorder

Importance

Bipolar disorder (BD) is highly familial and characterized by deficits in reward processing. It is not known, however, whether these deficits precede illness onset or are a consequence of the disorder.

Objective

To determine whether anomalous neural processing of reward characterizes children at familial risk for BD in the absence of a personal history of a psychopathologic disorder.

Design, Setting, and...