Challenges in Development of Targeted Liposomal Therapeutics
Abstract
Liposomes, phospholipid vesicles with a bilayered membrane structure, have been widely used as pharmaceutical carriers for drugs and genes, in particular for treatment of cancer. To enhance the efficacy of the liposomal drugs, drug-loaded liposomes are targeted to the tumors by means of passive (enhanced permeability and retention mediated) targeting, based on the longevity of liposomes in blood and its accumulation in pathological sites with...
Paper Details
Title
Challenges in Development of Targeted Liposomal Therapeutics
Published Date
Mar 14, 2012
Journal
Volume
14
Issue
2
Pages
303 - 315
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