The plasma bradykinin-forming pathways and its interrelationships with complement
Abstract
The plasma bradykinin-forming cascade and the complement pathways share many elements, including cross-activation, common control mechanisms, and shared binding proteins. The C1 inhibitor (C1 INH) is not only the inhibitor of activated C1r and C1s, but it is the key control protein of the plasma bradykinin-forming cascade. It inhibits the autoactivation of Factor XII, the ability of Factor XIIa to activate prekallikrein and Factor XI, the...
Paper Details
Title
The plasma bradykinin-forming pathways and its interrelationships with complement
Published Date
Aug 1, 2010
Journal
Volume
47
Issue
13
Pages
2161 - 2169
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