Proteomic analysis of EZH2 downstream target proteins in hepatocellular carcinoma
Abstract
Enhancer of zeste homolog 2 (EZH2) is suggested to be a potential therapeutic target and a diagnostic marker for cancer. Our previous study also showed the critical role of EZH2 in hepatocellular carcinoma (HCC) tumorigenesis. The present study is aimed at revealing the comprehensive downstream pathways of EZH2 by functional proteomic profiling. Lentivirus mediated RNA interference (RNAi) was employed to knockdown EZH2 in HCC cells. The 2‐DE was...
Paper Details
Title
Proteomic analysis of EZH2 downstream target proteins in hepatocellular carcinoma
Published Date
Sep 1, 2007
Journal
Volume
7
Issue
17
Pages
3097 - 3104
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