A novel Alzheimer disease locus located near the gene encoding tau protein
Abstract
APOE ɛ4, the most significant genetic risk factor for Alzheimer disease (AD), may mask effects of other loci. We re-analyzed genome-wide association study (GWAS) data from the International Genomics of Alzheimer's Project (IGAP) Consortium in APOE ɛ4+ (10 352 cases and 9207 controls) and APOE ɛ4- (7184 cases and 26 968 controls) subgroups as well as in the total sample testing for interaction between a single-nucleotide polymorphism (SNP) and...
Paper Details
Title
A novel Alzheimer disease locus located near the gene encoding tau protein
Published Date
Jan 1, 2016
Journal
Volume
21
Issue
1
Pages
108 - 117
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